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New warning for Ozempic-style drugs over risk of suicidal thoughts
The TGA has issued a new safety warning for GLP-1-based drugs including Ozempic. (ABC News: Phil Hemingway)
The Therapeutic Goods Administration has released a new safety alert for glucagon-like peptide-1 medications.
GLP-1-based medications include the likes of Ozempic, Wegovy and Mounjaro, which have increasingly been used to manage type 2 diabetes and obesity.
The TGA says patients taking the affected medicines should tell their doctor if they experience changes in mood or behaviour.
Australia's medicines regulator has issued a safety warning over the potential risk of suicidal thoughts and behaviours when taking Ozempic-style drugs.
The Therapeutic Goods Administration (TGA) released a safety alert on Monday, saying it had updated product warnings for GLP-1-based drugs to "ensure consistent information regarding the potential risk of suicidal thoughts or behaviours".
Australia’s drug regulator issues mental health warning for weight-loss drugs including Ozempic
TGA issues a separate warning for Mounjaro about risk of reduced effectiveness of contraception
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The medicines regulator has added two new safety warnings about mental health and contraception for people taking high-profile diabetes and weight loss drugs.
While there is no proof of a causal association, experts say the risks are significant enough that awareness is important as part of a precautionary approach.
The Therapeutic Goods Administration (TGA) says that because suicidal behaviour and ideation have been reported with these relatively new GLP-1 receptor agonists, doctors should “monitor patients for the emergence or worsening of depression, suicidal thoughts or behaviours, and/or any unusual changes in mood or behaviourâ€.
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